Founding Metamorphosis-Tx
December 20, 2023. Metamorphosis-Tx was founded as a subsidiary of DCDC-Tx. Metamorphosis is dedicated to develop cancer differentiation therapy. BioDetection Systems (BDS) is co-founder of Metamorphosis.
CALUX-STP technology of BDS complements STAP-STP technology of DCDC-Tx.
This allows new drug development and drug repurposing.
Team
Clinical, cell biology/molecular biology, stem cell biology, preclinical/clinical drug development, IP, legal, business expertise
founder, CSO (Chief Scientific Officer): Anja van de Stolpe
Dr. Anja van de Stolpe is an internist with clinical, translational, preclinical drug repurposing, and entrepreneurial experience. PhD degree in cell and molecular biology at the Hubrecht Institute (Utrecht, The Netherlands), post-doc at Stanford University.
She is an inventor on a large number of patents, including the STP portfolio.
For publications, see Selected Publications and ResearchGate. For CV details, see LinkedIn.
FOUNDER, COO (CHIEF OPERATING OFFICER): BRAM BROUWER
Chief Operational Officer: Em. Professor Abraham Brouwer, CEO BDS, studied Chemistry in Leiden and obtained a PhD in Medicine; he has over 30 years of experience as licensed toxicologist and held a chair position in Environmental Toxicology and Ecogenomics at VU University Amsterdam. He is the inventor of the CALUX technology. For CV and publications, see LinkedIn and ResearchGate.
FOUNDER, CMO (Chief Medical Officer): Reinier Raymakers
Dr Reinier Raymakers is a clinical hematologist, with focus on hemato-oncology, with extensive translational research (11 PhD theses), and clinical drug development experience.
PhD degree on Autologous Bone Marrow Transplantation for malignancies, post-doc at Roswell Park Cancer Institute (Buffalo, NY) and University Medical Center Leiden (The Netherlands). Clinical staff member at the academic hematology department UMC Radboud and UMC Utrecht. For publications, see Selected Publications and ResearchGate. For CV details, see LinkedIn.
FOUNDER, acting CEO: Frans Bos, PhD Physics, LLM
Extensive managerial experience at Executive level in a broad portfolio of fields
FOUNDER, CFO: YVETTE VAN SCHEPPINGEN
LABORATORY: TJALF DE BOER, PROJECT LEADER
LABORATORY: CLEMENCE BUDIN, PRINCIPLE INVESTIGATOR
Clémence studied Engineering with a major in Biology (Polytech Clermont-Ferrand) and completed her PhD in Toxicology at the Vrije Universiteit Amsterdam. She has experience in the development and application of biotechnologies. For CV and publications, see LinkedIn and ResearchGate, Google Scholar.
Legal adviser: Jan Karel van der Staay, LLM
Former General Counsel. Extensive governance, legal and M&A experience at Board level. For CV details, see LinkedIn.
BUSINESS ADVISER: MARC RENNE
Marc Renne studied Business Economics in Rotterdam and INSEAD in Fontainebleau. Marc joined Nimbus in 2001 as partner and co-founder, focused at turnaround management; extensive commercial and financial expertise. For CV details, see Linkedin.
Advisory board
Metamorphosis Tx has an informal international clinical and scientific advisory board, providing state-of-the-art relevant expertise on demand.